Valentina Redinciuc, Aurica P. Chiriac and Vera Balan Pages 95 - 99 ( 5 )
Background: As long as breast cancer is one of the leading cancers for women in the world, it is understandable and has justified the interest for studies in medicine to lead to an increase in demand for materials that can fulfill specific functions to enhance the therapeutic effects.Objective: The review is focused on the research and the current progress in the development of self-assembled structures based on natural and/or synthetic polymers, functionalized or not with various targeting molecules, focusing especially on the recent publications and patents that describe these nanostructures and highlight their potential applications in breast cancer therapy. Conclusion: The paper may help in designing better therapy for the evasion of efflux pumps in the cancer cells and to overcome resistance to chemotherapeutic agents which is a major impediment in the treatment of various types of cancers including breast cancer.
Biomedical applications, breast cancer, nanoparticles, patents, polymers, self-assembly.
Petru Poni Institute of Macromolecular Chemistry, Grigore Ghica Voda Alley 41A, 700487, Iasi